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Amblyopia is decreased vision in one or both eyes due to abnormal development of vision in infancy or childhood. In amblyopia, there may not be an obvious problem of the eye. Vision loss occurs because nerve pathways between the brain and the eye aren’t properly stimulated. The brain “learns” to see only blurry images with the amblyopic eye even when glasses are used. As a result, the brain favors one eye, usually due to poor vision in the other eye. Another word for amblyopia is often “lazy eye.” It is the leading cause of vision loss amongst children.
Normal vision develops during the first few years of life. At birth infants, have very poor vision, however as they use their eyes the vision improves because the vision centers in the brain are developing. If infants are not able to use their eyes from various reasons the vision centers do not develop properly and the vision is decreased despite normal appearance of the structures of the eyes.
The most common cause is refractive error in one or both eyes that is not corrected early in childhood resulting in poor development of the visual function in the affected eye/s. This is called refractive amblyopia.
Another common cause is strabismus or eye misalignment. This is called strabismic.
Rarely there is a structural anomaly that impairs the visual function like a droopy eyelid or opacity in the visual axis like cataract or corneal scar. This is called deprivation amblyopia.
Multiple causative factors can coexist.
Glasses may improve visual acuity to some degree but usually not completely. With amblyopia, the brain is “used to” seeing a blurry image and needs to learn how to see better with that eye.. With time, however, the brain may “re-learn” how to see and the vision may increase. The normal eye is treated (most often with patching or eyedrops) to make the amblyopic (weak) eye stronger.
Early treatment is always best. If necessary, children with refractive errors (nearsightedness, farsightedness or astigmatism) can wear glasses or contact lenses when they are as young as one week old. Children with cataracts or other “amblyogenic” conditions are usually treated promptly in order to minimize the development of amblyopia.
One of the most important treatments of amblyopia is correcting the refractive error with consistent use of glasses and/or contact lenses. Other mainstays of amblyopia treatment are to enable as clear an image as possible (for example, by removing a cataract), and forcing the child to use the weaker eye (via patching or eye drops to blur the better-seeing eye).